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Living forever may be far fetched and beyond your control now, but science is coming closer to making it easier and more possible to live a longer healthier life. In this episode, find out how to reverse aging, prevent cancer, and delay the aging process with Peter Attia, Mike Mutzel, Jimmy Moore and David Sinclair. Becoming a “kick ass 100 year old” through fitness, body movement, understanding diet and fasting cycles is closer, more practical, achievable and affordable than you may think.
Cellular Aging | What the epigenome’s role is in cellular function that contributes to aging [1:40]
DNA Packaging | Making enzymes needed for DNA packaging and repair more active [5:39]
Biological Age | The DNA clock that tells your age and approximate age of death [9:15]
Regulating Aging | Pathways that regulate aging and how Metformin helps create energy [11:42]
Diet & Fasting | Why having variety is best and knowing when too much is too much [14:57]
Fasting | Effective fasting cycles and frequency to get the most benefit [20:24]
Anti-Cancer | Effects of fasting on potential cancer properties and how insulin ties in [30:10]
Fit at 100 | Peter Attia redefines what fitness should look like to be functional in old age [34:36]
Cold Exposure | Why cryotherapy is beneficial and how it builds brown fat [44:03]
Longevity Diet | Mike Mutzel explains why eating the same time everyday is critical [46:55]
Biomarkers | These are some of the biomarkers to pay attention to and why they matter [50:55]
Metformin | Mike explains how this interacts with the microbiome and affects autophagy [55:28]
Methylation Clock | David explains reverse aging is becoming a reality being explored [57:50]
“…aging is caused because cells lose their packaging. And then eventually cells lose their identity, disease ensues. Cells check out, they become zombie-like, and then our organs fail and we die.” David Sinclair [4:50]
“I think when it’s too much is when it affects your sleep, when it affects your recovery, and your muscle performance. When you start seeing negative side effects. When is it ideal? When you feel good.” Mike Mutzel [18:33]
“ In other words, the worse the diet, the better the benefit of caloric restriction, which points us to this idea that dietary restriction should still always be some component of a healthy nutrition strategy.” Peter Attia [26:17]
“I would rather be poor, but know how to […] live longer, than have all the money in the world and lose my health.” Peter Attia [27:10]
“So people start saying, I have MS, I have this, and I think we need to realize that certainly our body can have perturbations, but it doesn’t mean you’re always going to manifest symptoms of that if you can. The body and the mind and the diet and lifestyle are so powerful.” Mike Mutzel [34:09]
“I don’t really care so much as what you eat, and how much I want you eating at the same time every day, whatever that is.” Mike Mutzel [47:21]
David Sinclair, Ph.D. is a Harvard professor best known for his work on delaying and reverse aging. He is the author of the NYT bestseller, Lifespan: Why We Age and Why We Don’t Have To
Peter Attia earned his M.D. from Stanford University and specializes in the applied science of longevity. He focuses on many areas including emotional and mental health, pharmacology to increase lifespan (how long you live), and improving healthspan (the quality of your life).
Mike Mutzel is at the forefront of functional medicine. His top-rated podcasts have helped thousands of people with fitness, nutrition, and general health advice. He focuses on low-carb (ketogenic) diets, gut bacteria health, sleep, and building muscle.
Jimmy Moore is the bestselling author of Keto Clarity and host of the long-running Livin’ La Vida Low Carb Podcast. He specializes in the keto lifestyle (low-carb, high-fat, ketogenic).
FOLLOW DAVID SINCLAIR: https://www.linkedin.com/in/sinclairda
FOLLOW PETER ATTIA: https://peterattiamd.com/
FOLLOW MIKE MUTZUL: https://highintensityhealth.com/
FOLLOW JIMMY MOORE: https://livinlavidalowcarb.com/